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Cancer stem cells the target in new clinical trial
By admin at 2013-07-03 22:47
 

Breast cancer often returns as chemotherapyterm is designed to target the tumor but not the cancer stem cells that are often the root of the disease.


It is this focus that drives a new clinical trial open now at Michigan Comprehensive Cancer Center and two more sites. Reparixin will be used in combination with standard chemotherapy.


read more | 3856 reads

Oral HPV in Men
By admin at 2013-07-03 22:41
 

Smokers and single men are more likely to acquire cancer-causing oral human papillomavirus (HPV), according to new results from the HPV Infection in Men (HIM) Study. Researchers from Moffitt Cancer Center, the National Cancer Institute, Mexico and Brazil also report that newly acquired oral HPV infections in healthy men are rare and when present, usually resolve within one year.


The study results appeared in the July issue of The Lancet.

read more | 3194 reads

Immune-boosting colorectal cancer drug shows promise
By admin at 2013-07-03 22:38
 

An emerging treatment that aims to fight colorectal cancer by stimulating the immune system have been presented at the ESMO 15th World Congress on Gastrointestinal Cancer.



The drug is MGN1703 and it may be possible to identify which gastrointestinal cancer patients will benefit most from the treatment, reported Prof Hans-Joachim Schmoll from Martin Luther University, Halle, Germany.

read more | 1 comment | 3129 reads

Non hormonal therapy for hot flashes and night sweats
By admin at 2013-07-03 22:31
 

The FDA has approved a non hormonal therapy for hot flashes, potentially providing relief for patients with ER positive breast tumors or the concenrn of such.

read more | 2500 reads

Immune system to fight brain tumors
By Dross at 2013-05-31 00:35
 

Research at Lund University in Sweden gives hope that one of the most serious types of brain tumour, glioblastoma multiforme, could be fought by the patients' own immune system. The tumours are difficult to remove with surgery because the tumour cells grow into the surrounding healthy brain tissue. A patient with the disease therefore does not usually survive much longer than a year after the discovery of the tumour. The team has tested different ways of stimulating the immune system, suppressed by the tumour, with a 'vaccine'.

 

read more | 6 comments | 3236 reads

Sweeping Study Of Cancer Metabolism Identifies Hundreds Of Alterations And Potential Drug Targets To Starve Tumors
By gdpawel at 2013-05-02 14:06
 
 
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, also identified hundreds of potential drug targets that could cut off a tumor's fuel supply or interfere with its ability to synthesize essential building blocks.

read more | 2 comments | 3571 reads

Leading leukemia experts: High leukemia treatment costs may be harming patients
By Dross at 2013-04-26 00:29
 

 The increasing cost of treatments for chronic myeloid leukemiaterm (CML) in the United States has reached unsustainably high levels and may be leaving many patients under- or untreated because they cannot afford care, according to a Blood Forum article supported by nearly 120 CML experts from more than 15 countries on five continents and pu

read more | 3315 reads

Researchers Identify New Pathway, Enhancing Tamoxifen to Tame Aggressive Breast Cancer
By Dross at 2013-04-24 23:48
 

Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen’s secondary activities so that it

read more | 1 comment | 3334 reads

Virus kills melanoma in animal model, spares normal cells
By admin at 2013-04-24 22:56
 

Researchers from Yale University School of Medicine have demonstrated that vesicular stomatitis virus (VSV) is highly competent at finding, infecting, and killing human melanoma cells, both in vitro and in animal models, while having little propensity to infect non-cancerous cells.



"If it works as well in humans, this could confer a substantial benefit on patients afflicted with this deadly disease," says Anthony van den Pol, a researcher on the study. The research was published online ahead of print in the Journal of Virology.

read more | 2616 reads

Screening breast ultrasound detects cancers missed on mammography in women with dense breasts
By Dross at 2013-04-18 22:02
 

Screening breast ultrasound performed after mammography on women with greater than 50% breast density detects an additional 3.4 cancers or high risk lesions per one thousand woman screened, a detection rate just under that of screening mammography alone for women with less dense breasts, a new study shows. Screening mammography detects 4-5 cancers per thousand women screened.

read more | 1 comment | 2526 reads

New ablation technique holds promise for liver cancer patients
By Dross at 2013-04-18 21:55
 

A new minimally invasive tumor ablation technique is providing hope for liver cancer patients who can't undergo surgery or thermal ablation, a study shows.

The study of 22 patients at the Universitatsklinikum Regensberg in Regensberg, Germany, found that irreversible electroporation (IRE) successfully destroyed tumor tissue in 70% of these patients.

read more | 2 comments | 2780 reads

CT and serum LDH shows promise as survival predictor for some metastatic melanoma patients
By Dross at 2013-04-17 18:05
 

Combining CT imaging findings with baseline serum lactate dehydrogenase levels is showing promise as a way to predict survival in patients with metastaticterm melanoma being treated with anti-angiogenic therapy.

read more | 2944 reads

Circadian Rhythm and the Myc oncogene.
By Dross at 2013-04-10 07:49
 

The Myc oncogene can disrupt the 24-hour internal rhythm in cancer cells. Postdoctoral fellow Brian Altman, PhD, and graduate student Annie Hsieh, MD, both from the in the lab of Chi Van Dang, MD, PhD, director of the Abramson Cancer Center, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, present their data in the "Metabolic Pathway Regulation in Cancer" session at the 2013 American Association for Cancer Research meeting, Washington, D.C., April 9, 2013.

read more | 3 comments | 1697 reads

Brighton researchers' discovery may prolong cancer patients’ lives
By gdpawel at 2013-03-20 08:57
 

Cancer patients around the world could have their lives extended thanks to a discovery made by Sussex scientists.

Researchers at the University of Sussex, who have been working with the Institute of Cancer Research, have found that a cutting-edge cancer drug may be able to keep patients alive for longer than they live now.

The discovery by the researchers, who looked at exactly how the drugs attack tumours, has been hailed as “unexpected and exciting”.

The drugs, known as kinase inhibitors, are a new type of treatment, with 25 currently in use on a variety of cancers.

read more | 5 comments | 1866 reads

For Smokers, Low Levels of Vitamin D May Lead to Cancer
By Dross at 2013-03-16 05:26
 

New research appearing online today in Clinical Chemistry, the journal of AACC, shows that decreased levels of vitamin D may predispose smokers to developing tobacco-related cancer. This study illustrates that simple vitamin D blood tests and supplements have the potential to improve smokers' health.  In the U.S. alone, cigarette smoking accounts for more deaths annually than HIV, illegal drugs, alcohol, motor vehicle injuries, suicides, and murders combined.

read more | 1 comment | 1612 reads

 
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