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Old 12-01-2007, 06:09 PM
Dross Dross is offline
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Default DNA methylation shown to promote development of colon tumors

A new story entry has been added:

DNA methylation shown to promote development of colon tumors

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CAMBRIDGE, Mass. (December 1, 2007) ? Damaged or defective genes have long been known to be the cause of some cancers. Over the past decade, however, scientists have discovered that even healthy genes can be switched on or off and can cause cancer without any changes in the underlying DNA sequence?although how this happens has remained poorly understood.
Researchers in the laboratory of Whitehead Member Rudolf Jaenisch now have established a direct causal connection between hypermethylation (the accumulation of too many methyl molecules on regions of DNA) and the development of colon tumors in mice.
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Old 12-01-2007, 08:43 PM
flux169 flux169 is offline
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I wonder is it safe to switch on or off the abnormal methylation pattern, just to reactivating the genes that suppress tumors.
They should be more carefull.
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