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Recent Forum Topics

 
Why Do Cancer Surgeons Cure More Patients Than Medical Oncologists?
By gdpawel at 2014-04-09 19:23
 

 

Robert A. Nagourney, M.D.

 

Who does it really serve when a clinical trial involving 597 patients results in an increase in survival by 10 days?

 

read more | 3 comments | 3 reads

Whole genome sequencing; not ready for prime time
By gdpawel at 2014-03-14 06:06
 
A test of the utility of whole-genome sequencing (WGS) on 12 genetically healthy adults reveals several shortcomings, according to a study published in the March 12 issue of JAMA.
read more | 3 comments | 314 reads

Microarray, Gene Expression and Cell-Lines
By gdpawel at 2014-01-14 15:10
 
 
There have been attempts to develop molecular-based tests to examine a broader range of chemotherapeutic drugs. New technologies for measuring the expression (biological activity) of literally hundreds to thousands of genes as part of a single test.

read more | 1 comment | 962 reads

The Downside To Clinical Trials
By gdpawel at 2014-01-14 08:45
 

 

As the practice of medicine has moved from a profession to an industrial undertaking, this most human of experiences has fallen prey to the dictates of the American business model. Patients are no longer the purchasers of medical care and services, but instead, the consumers of those goods and services that meet the needs of the purveyors. Whether this is a governmental entity, academic institution, or pharmaceutical company, individuals have become cogs in the wheel of the medical-industrial complex.

read more | 6 comments | 949 reads

Test Shown to Reduce Early Cancer Deaths is Now Available to Patients
By gdpawel at 2013-11-16 07:37
 

Huntington Beach, CA - SignatureCLL today announced that the first laboratory test ever shown in a clinical trial to improve one year survival rates in cancer is now available to patients with chronic lymphocytic leukemiaterm (also called CLL).

 

read more | 1337 reads

Cell Biology
By gdpawel at 2013-10-17 12:43
 

On October 7, 2013, in Stockholm, Sweden, the Nobel Committee announced the winners of the Nobel Prize for Medicine and Physiology – two Americans and one German, all now located at institutions in the US. The discovery for which these three investigators share the prize involves their work over three decades studying the transport, packaging and trafficking of cellular proteins.

 

read more | 2097 reads

An answer to chemobrain
By admin at 2013-09-19 04:30
 

A team from the University of Rochester Medical Center has shown scientifically what many women report anecdotally: that the breast cancer drug tamoxifen is toxic to cells of the brain and central nervous system, producing mental fogginess similar to “chemo brain.”


However, in the Journal of Neuroscience, researchers also report they’ve discovered an existing drug compound that appears to counteract or rescue brain cells from the adverse effects of the breast cancer drug.

read more | 1440 reads

Next 'Cure for Cancer' Lost to Sequester
By gdpawel at 2013-09-19 02:54
 

 

Billions of dollars in research funding and thousands of health-related jobs have been lost to the sequester, putting the nation's healthcare system at risk, said panelists speaking at a health forum last week.

 

National Institutes of Health Director Francis Collins, MD, said his institute has lost $1.7 billion in federal funding since the start of sequestration and stands to lose another $600 million on October 1.

 

read more | 1663 reads

New target combined with Tamoxifen aids in ER-positive breast cancers
By Dross at 2013-07-09 00:44
 
Researchers have identified compounds used in some leukemiaterm treatments that may have an application towards ER positive breast cancer that is unresponsive to traditional treatments. 
The discovery was made at the Walter and Eliza Hall Institute. BH-3 mimetics were effective in treating aggressive oestrogen receptor-positive breast cancers when combined with the breast cancer drug tamixifen in preclinical models. Approximately 70 per cent of breast cancers are ER positive. 
read more | 1 comment | 2720 reads

Targeting errant immune system enzyme kills myelodysplastic cells
By Dross at 2013-07-09 00:24
 

Scientists have successfully targeted a malfunctioning immune system enzyme to kill diseased cells from patients with myelodysplastic syndrome (MDS) -- a blood disorder and precursor to leukemiaterm. Reporting their results July 8 in Cancer Cell, researchers say their successful laboratory tests in human MDS cells and mouse models of MDS provide a molecular target for designing new drugs to battle a syndrome with few effective treatments.

read more | 2334 reads

A Phase II Study in Previously Treated Locally Advanced and Metastatic Triple-Negative Breast Cancer
By admin at 2013-07-03 22:57
 

A Phase II Study of the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced and Metastaticterm Triple-Negative Breast Cancer


http://www.clinicaltrials.gov/ct2/show/NCT01639248?term=triple+negative+breast+cancer+colorado&rank=1



Criteria

read more | 2711 reads

Cancer stem cells the target in new clinical trial
By admin at 2013-07-03 22:47
 

Breast cancer often returns as chemotherapyterm is designed to target the tumor but not the cancer stem cells that are often the root of the disease.


It is this focus that drives a new clinical trial open now at Michigan Comprehensive Cancer Center and two more sites. Reparixin will be used in combination with standard chemotherapy.


read more | 2097 reads

Oral HPV in Men
By admin at 2013-07-03 22:41
 

Smokers and single men are more likely to acquire cancer-causing oral human papillomavirus (HPV), according to new results from the HPV Infection in Men (HIM) Study. Researchers from Moffitt Cancer Center, the National Cancer Institute, Mexico and Brazil also report that newly acquired oral HPV infections in healthy men are rare and when present, usually resolve within one year.


The study results appeared in the July issue of The Lancet.

read more | 1981 reads

Immune-boosting colorectal cancer drug shows promise
By admin at 2013-07-03 22:38
 

An emerging treatment that aims to fight colorectal cancer by stimulating the immune system have been presented at the ESMO 15th World Congress on Gastrointestinal Cancer.



The drug is MGN1703 and it may be possible to identify which gastrointestinal cancer patients will benefit most from the treatment, reported Prof Hans-Joachim Schmoll from Martin Luther University, Halle, Germany.

read more | 1 comment | 2102 reads

Non hormonal therapy for hot flashes and night sweats
By admin at 2013-07-03 22:31
 

The FDA has approved a non hormonal therapy for hot flashes, potentially providing relief for patients with ER positive breast tumors or the concenrn of such.

read more | 2016 reads

 
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